Follow the diluent your prescriber or the product labeling specifies
Central to this shift is the recognition that intestinal reparative therapy, defined by objective endpoints such as endoscopic and histologic healing, is strongly associated with improved long-term outcomes
Additionally, GLP-1 RAs have shown potential in mitigating inflammation in diabetic kidney disease by inhibiting angiotensin II signaling, downregulating the receptor for advanced glycation end products, attenuating myelopoiesis, and promoting M2 macrophage polarization in mouse models [65, 66]
Main exclusion criteria included recent gastrointestinal discomfort (e.g., abdominal pain or diarrhea) within the previous month, recent use of antibiotics, use of probiotics or prebiotics within the previous month, and advanced chronic kidney disease or other metabolic disorders (thyroid dysfunction, Cushing syndrome, acromegaly, and pheochromocytoma)
Lvesque LE, Hanley JA, Kezouh A, Suissa S